anti-human cd1a fitc (clone hi149) (Thermo Fisher)
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anti-human cd1a fitc (clone hi149)
Anti Human Cd1a Fitc (Clone Hi149), supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti-human+cd1a+fitc+(clone+hi149)/cd1a+antibody/pm40233759-297-2-10
Average 90 stars, based on 1 article reviews
Anti Human Cd1a Fitc (Clone Hi149), supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti-human+cd1a+fitc+(clone+hi149)/cd1a+antibody/pm40233759-297-2-10
Average 90 stars, based on 1 article reviews
anti-human cd1a fitc (clone hi149) - by Bioz Stars,
2026-10
90/100 stars
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Recombinant:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Sequencing:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Transgenic Assay:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Software:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Incubation:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Bioprocessing:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Control:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Staining:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. Expressing:Article Title: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis. Article Snippet: REAGENT or Article Title: Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Article Snippet: Accepted Manuscript Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl PII: S0887-2333(17)30271-0 DOI: doi: 10.1016/j.tiv.2017.09.019 Reference: TIV 4120 To appear in: Toxicology in Vitro Received date: 23 December 2016 Revised date: 9 September 2017 Accepted date: 19 September 2017 Please cite this article as: Stephanie Bock, André Said, Gerrit Müller, Monika SchäferKorting, Christian Zoschke, Günther Weindl , Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization, Toxicology in Vitro (2017), doi: 10.1016/j.tiv.2017.09.019 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Article Snippet: Article Title: Role of Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells in the Recognition of Hepatitis B Virus. Article Snippet: Dendritic cell–specific ICAM-3-grabbing nonintegrin (DC-SIGN) is an essential process for virus infection, such as HIV and hepatitis C, and plays a role in immune escape.. However, the role of DC-SIGN in hepatitis B virus (HBV) infection is still unknown.. The aim of this study was to investigate the role of DC-SIGN in mediating the maturation and activation of dendritic cells (DCs) when infected by HBV. Article Title: Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. Article Snippet: Background: As mediators between innate and adaptive immune responses, Langerhans cells (LCs) are in the focus of recent investigations to determine their role in allergic inflammatory diseases like allergic contact dermatitis and atopic dermatitis.. Sphingosine 1-phosphate (S1P) is a crucial lipid mediator in the skin and potentially interferes with LC homeostasis but also functional properties, such as cytokine release, migration and antigen-uptake which are considered to be key events in the initiation and maintenance of pathological disorders.. Objective: Here, we used human Langerhans-like cells to study the influence of S1P-mediated signalling on LC maturation, cytokine release, migration and endocytosis. |